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1

Human Genetic Determinants of Viral Diseases

Kenney, Adam D., Dowdle, James A., Bozzacco, Leonia, McMichael, Temet M., St. Gelais, Corine, Panfil, Amanda R., Sun, Yan, Schlesinger, Larry S., Anderson, Matthew Z., Green, Patrick L., López, Caroli

Journal:

Annual Review of Genetics

Year:

2017

Language:

english

File:

PDF, 602 KB

english, 2017

2

SAMHD1: a new insight into HIV-1 restriction in myeloid cells

Corine St Gelais, Li Wu

Journal:

Year:

2011

Language:

english

File:

PDF, 685 KB

english, 2011

3

SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+T-lymphocytes cannot be upregulated by interferons

Corine St Gelais, Suresh de Silva, Sarah M Amie, Christopher M Coleman, Heather Hoy, Joseph A Hollenbaugh, Baek Kim, Li Wu

Journal:

Year:

2012

Language:

english

File:

PDF, 511 KB

english, 2012

4

Phosphorylation of mouse SAMHD1 regulates its restriction of human immunodeficiency virus type 1 infection, but not murine leukemia virus infection

Wang, Feifei, St. Gelais, Corine, de Silva, Suresh, Zhang, Hong, Geng, Yu, Shepard, Caitlin, Kim, Baek, Yount, Jacob S., Wu, Li

Journal:

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

5

Non-POU Domain-Containing Octamer-Binding Protein Negatively Regulates HIV-1 Infection in CD4 + T Cells

St. Gelais, Corine, Roger, Jonathan, Wu, Li

Journal:

AIDS Research and Human Retroviruses

Year:

2015

Language:

english

File:

PDF, 722 KB

english, 2015

6

SAMHD1 controls cell cycle status, apoptosis and HIV-1 infection in monocytic THP-1 cells

Bonifati, Serena, Daly, Michele B., St. Gelais, Corine, Kim, Sun Hee, Hollenbaugh, Joseph A., Shepard, Caitlin, Kennedy, Edward M., Kim, Dong.-Hyun., Schinazi, Raymond F., Kim, Baek, Wu, Li

Journal:

Year:

2016

Language:

english

File:

PDF, 561 KB

english, 2016

7

SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity

Antonucci, Jenna M, St. Gelais, Corine, de Silva, Suresh, Yount, Jacob S, Tang, Chenxiang, Ji, Xiaoyun, Shepard, Caitlin, Xiong, Yong, Kim, Baek, Wu, Li

Journal:

Nature Medicine

Year:

2016

Language:

english

File:

PDF, 817 KB

english, 2016

8

A Putative Cyclin-binding Motif in Human SAMHD1 Contributes to Protein Phosphorylation, Localization and Stability

St. Gelais, Corine, Kim, Sun Hee, Ding, Lingmei, Yount, Jacob, Ivanov, Dmitri, Spearman, Paul, Wu, Li

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.85 MB

english, 2016

9

HIV-1 exploits dynamic multi-aminoacyl-tRNA synthetase complex to enhance viral replication

Duchon, Alice A., St-Gelais, Corine, Titkemeier, Nathan, Hatterschide, Joshua, Wu, Li, Musier-Forsyth, Karin

Journal:

Journal of Virology

Year:

2017

Language:

english

File:

PDF, 1.79 MB

english, 2017

10

A Cyclin-binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation

St. Gelais, Corine, Kim, Sun Hee, Maksimova, Victoria V., Buzovetsky, Olga, Knecht, Kirsten, Shepard, Caitlin, Kim, Baek, Xiong, Yong, Wu, Li

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 3.62 MB

english, 2018

11

SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways

Chen, Shuliang, Bonifati, Serena, Qin, Zhihua, St. Gelais, Corine, Kodigepalli, Karthik M., Barrett, Bradley S., Kim, Sun Hee, Antonucci, Jenna M., Ladner, Katherine J., Buzovetsky, Olga, Knecht, Kirs

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.44 MB

english, 2018

12

SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4 + T-cells

Antonucci, Jenna M., Kim, Sun Hee, St. Gelais, Corine, Bonifati, Serena, Li, Tai-Wei, Buzovetsky, Olga, Knecht, Kirsten M., Duchon, Alice A., Xiong, Yong, Musier-Forsyth, Karin, Wu, Li

Journal:

Journal of Virology

Year:

2018

Language:

english

File:

PDF, 3.25 MB

english, 2018

13

HIV-1 Nef Enhances Dendritic Cell-Mediated Viral Transmission to CD4+ T Cells and Promotes T-Cell Activation

St. Gelais, Corine, Coleman, Christopher M., Wang, Jian-Hua, Wu, Li, Wu, Yuntao

Journal:

Year:

2012

Language:

english

File:

PDF, 1.98 MB

english, 2012

14

N 6 -methyladenosine-binding proteins suppress HIV-1 infectivity and viral production

Lu, Wuxun, Tirumuru, Nagaraja, St.Gelais, Corine, Koneru, Pratibha C., Liu, Chang, Kvaratskhelia, Mamuka, He, Chuan, Wu, Li

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 1.19 MB

english, 2018

15

The Dynamic Interplay between HIV-1, SAMHD1, and the Innate Antiviral Response

Antonucci, Jenna M., St. Gelais, Corine, Wu, Li

Journal:

Frontiers in Immunology

Year:

2017

Language:

english

File:

PDF, 1.15 MB

english, 2017

16

SAMHD1 Suppression of Antiviral Immune Responses

Chen, Shuliang, Bonifati, Serena, Qin, Zhihua, St. Gelais, Corine, Wu, Li

Journal:

Trends in Microbiology

Year:

2018

Language:

english

File:

PDF, 1.96 MB

english, 2018

17

The dNTPase activity of SAMHD1 is important for its suppression of innate immune responses in differentiated monocytic cells

Qin, Zhihua, Bonifati, Serena, St.Gelais, Corine, Li, Tai-Wei, Kim, Sun-Hee, Antonucci, Jenna Marie, Mahboubi, Bijan, Yount, Jacob S., Xiong, Yong, Kim, Baek, Wu, Li

Journal:

Journal of Biological Chemistry

Year:

2019

Language:

english

File:

PDF, 9.66 MB

english, 2019

18

TRAF6 and TAK1 contribute to SAMHD1-mediated negative regulation of NF-ÎºB signaling

Espada, Constanza E., St. Gelais, Corine, Bonifati, Serena, Maksimova, Victoria V., Cahill, Michael P., Kim, Sun Hee, Wu, Li

Journal:

Journal of Virology

Year:

2020

File:

PDF, 4.30 MB

2020